Investigaciones sobre los efectos del hidrógeno en la salud
Hígado graso e hidrógeno
Wang, X., & Wang, J. (2018). High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3. Biological chemistry, 399(4), 397-406.
Daño intestinal por radioterapia e hidrógeno
Xiao, H. W., Li, Y., Luo, D., Dong, J. L., Zhou, L. X., Zhao, S. Y., … & Fan, S. J. (2018). Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota. Experimental & molecular medicine, 50(1), e433-e433.
Infección viral e hidrógeno
Yang, M., Zhang, Z., Gao, B., Liu, L., & Hu, T. (2017). Hydrogen Medicine Therapy: An Effective and Promising Novel Treatment for Multiple Organ Dysfunction Syndrome (MODS) Induced by Influenza and Other Viral Infections Diseases?.
Fatiga e hidrógeno
Ara, J., Fadriquela, A., Ahmed, M. F., Bajgai, J., Sajo, M. E. J., Lee, S. P., … & Shim, K. Y. (2018). Hydrogen water drinking exerts antifatigue effects in chronic forced swimming mice via antioxidative and anti-inflammatory activities. BioMed research international, 2018.
Disfunción de vejiga e hidrógeno
Miyazaki, N., Yamaguchi, O., Nomiya, M., Aikawa, K., & Kimura, J. (2016). Preventive effect of hydrogen water on the development of detrusor overactivity in a rat model of bladder outlet obstruction. The Journal of urology, 195(3), 780-787.
Hidrógeno y reducción de daño oxidativo
Ohta S. Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases. Biochim Biophys Acta. 1820;2012:586–94.
Ohsawa I, Ishikawa M, Takahashi K, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med. 2007;13:688–94.
Parkinson e hidrógeno
Fujita K, Seike T, Yutsudo N, et al. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease. PLoS One. 2009;30:e7247.
Fu Y, Ito M, Fujita Y, et al. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson’s disease. Neurosci Lett. 2009;453:81–5.
Yoritaka A, Takanashi M, Hirayama M, Nakahara T, Ohta S, Hattori N. Pilot study of H2 therapy in Parkinson’s disease: A randomized double-blind placebo-controlled trial. Mov Disord. 2013;28:836–9.
Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992;55:181–4
Efectos benéficos del hidrógeno en la salud
Ichihara M, Sobue S, Ito M, Ito M, Hirayama M, Ohno K. Beneficial biological effects and the underlying mechanisms of molecular hydrogen—comprehensive review of 321 original articles. Med Gas Res. 2015;5:12.